Bis-PEG6-NHS ester
- Product NameBis-PEG6-NHS ester
- CAS1526718-98-8
- CBNumberCB63062418
- MFC24H36N2O14
- MW576.55
- MDL NumberMFCD24539464
- MOL File1526718-98-8.mol
Chemical Properties
solubility | Soluble in DMSO, DCM |
form | Viscous Liquid |
color | Colorless to light yellow |
Bis-PEG6-NHS ester Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
ChemScene CS-0107647 | 100mg | $230 | Bis-PEG6-NHSester ≥97.0% |
Buy |
BroadPharm BP-21681 | 100mg | $250 | Bis-PEG6-NHSester 98% |
Buy |
BroadPharm BP-21681 | 500mg | $350 | Bis-PEG6-NHSester 98% |
Buy |
ChemScene CS-0107647 | 250mg | $400 | Bis-PEG6-NHSester ≥97.0% |
Buy |
BroadPharm BP-21681 | 1g | $460 | Bis-PEG6-NHSester 98% |
Buy |
Bis-PEG6-NHS ester Chemical Properties,Usage,Production
Description
Bis-PEG6-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.Biological Activity
Bis-PEG6-NHS ester is a PROTAC bridge and belongs to the PEG class. It can be used to synthesize a range of PROTAC molecules. Also Bis-PEG6-NHS ester is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
Cleavable
| PEGs
| Alkyl/ether
|
Preparation Products And Raw materials
Bis-PEG6-NHS ester Supplier
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+1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
1526718-98-8, Bis-PEG6-NHS esterRelated Search
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