Description
As an organic acid, 2-Aminoisonicotinic acid (AN) can be grafted onto chitosan chains through amidation, thereby introducing 2-aminopyridine residues with good hydration capacity. Due to its specific chemical structure possessing push-pull effects and suitable length, 2-aminoisonicotinic acid is a promising ligand for the design of functional metal-organic frameworks. In addition, some studies demonstrated that the compounds bearing 2-aminopyridine residues showed good antibacterial activities. Given its functional characteristics, the grafting of 2-amino isonicotinic acid onto chitosan is expected to exhibit good water solubility and antibacterial activity and serve as an effective ligand to form stable chitosan?iodine complexes with iodine for antibacterial applications[1].
References
[1] Zhaoyu Zhang . “Chitosan?iodine complexes: Preparation, characterization, and antibacterial activity.” International Journal of Biological Macromolecules 260 (2024): Article 129598.
