Chemical Properties
Benzyltriphenylphosphonium Chloride is a white to off white powder, It is highly soluble in water and polarizable solvents. It is a quaternary phosphonium salt mainly used in organic synthesis as a wittig reagent and as a phase transfer catalyst in the production of fluoroelastomers and printing inks.
Uses
Benzyltriphenylphosphonium Chloride was used as a reagent in the organic synthesis of several compounds including that of stabilised phosphonium ylides containing saturated oxygen heterocycles. Also used in the synthesis of novel substituted cis-stilbene derivatives which display antimicrobial activity.
Application
Benzyltriphenylphosphonium chloride can be used as a reactant for the synthesis of:
Platinum chloro-tetrazole complexes via azidation.
Trans-stilbenes and cinnamates via Wittig olefination.
Achiral N-hydroxyformamide inhibitors of ADAM-TS4 and ADAM-TS5 for osteoarthritis treatment.
Pentiptycenes for use as light-driven molecular brakes.
Archipelago structures for formation of petroleum asphaltenes.
It is also used as a crosslinking agent for tube-like natural halloysite / fluorelastomer nanocomposites.
Crosslinking agent for tube-like natural halloysite / fluorelastomer nanocomposites
Reactant for synthesis of:
Platinum chloro tetrazole complexes via azidation
Trans-stilbenes and cinnamates via Wittig olefination
Achiral N-hydroxyformamide inhibitors of ADAM-TS4 and ADAM-TS5 for osteoarthritis treatment
Pentiptycenes for use as light-driven molecular brakes
Reactant for formation of archipelago structures for formation of petroleum asphaltenes
Purification Methods
Wash it with Et2O and crystallise it from EtOH (six-sided plates). It is hygroscopic and forms crystals with one molecule of H2O. [Michaelis & Soden Justus Liebigs Ann Chem 229 320 1885, Kr.hnke Chem Ber 83 291 1950, Beilstein 16 IV 994.]
