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Phentolamine mesilate

Phentolamine mesilate Structure
Phentolamine mesilate
  • CAS No.65-28-1
  • Chemical Name:Phentolamine mesilate
  • CBNumber:CB5708736
  • Molecular Formula:C18H23N3O4S
  • Formula Weight:377.46
  • MOL File:65-28-1.mol
Phentolamine mesilate Property
  • Melting point: :180-182 °C(lit.)
  • Density  :1.2256 (rough estimate)
  • refractive index  :1.6320 (estimate)
  • storage temp.  :2-8°C
  • solubility  :ethanol: 26 mg/mL
  • form  :powder
  • color  :white to off-white
  • Water Solubility  :50 mg/mL
  • Merck  :14,7264
  • Stability: :Aq. Solutions Cannot be Stored
  • InChIKey :OGIYDFVHFQEFKQ-UHFFFAOYSA-N
  • FDA UNII :Y7543E5K9T
  • NCI Drug Dictionary :phentolamine mesylate
Safety
  • Hazard Codes  :Xn,Xi
  • Risk Statements  :20/21/22-36/37/38
  • Safety Statements  :26-36
  • RIDADR  :3249
  • WGK Germany  :3
  • RTECS  :SL5430000
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • HS Code  :29332900
  • Toxicity :LDLo scu-rat: 275 mg/kg NIIRDN 6,667,82
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302+H312+H332-H315-H319-H335
  • Precautionary statements P261-P280-P305+P351+P338-P301+P312+P330
Phentolamine mesilate Price More Price(32)
  • Brand: Sigma-Aldrich
  • Product number: P7561
  • Product name : Phentolamine methanesulfonate salt
  • Purity: ≥98% (TLC), powder
  • Packaging: 100mg
  • Price: $94.3
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: Y0001251
  • Product name : Phentolamine mesilate for system suitability
  • Purity: European Pharmacopoeia (EP) Reference Standard
  • Packaging: 
  • Price: $190
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: Y0001127
  • Product name : Phentolamine mesilate
  • Purity: European Pharmacopoeia (EP) Reference Standard
  • Packaging: 
  • Price: $190
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1530004
  • Product name : Phentolamine mesylate
  • Purity: United States Pharmacopeia (USP) Reference Standard
  • Packaging: 200mg
  • Price: $366
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: P1985
  • Product name : Phentolamine Mesylate
  • Purity: >98.0%(HPLC)(T)
  • Packaging: 100mg
  • Price: $59
  • Updated: 2021/12/16
  • Buy: Buy

Phentolamine mesilate Chemical Properties,Usage,Production

  • Chemical Properties Crystalline Solid
  • Uses Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM
  • Uses Phentolamine Methanesulfonate Salt is an adrenergic blocking agent. An antihypertensive. Used for the treatment of pheochromocytoma.
  • Uses As an adrenergic blocking agent and an antihypertensive, Phentolamine mesilate can be used for the treatment of pheochromocytoma.
  • brand name Regitine (Novartis) [Name previously used: Phentolamine Methanesulfonate.].
  • General Description
    Phentolamine Mesylate belongs to the class of alpha adrenergic antagonist drugs. It is used in the treatment of pheochromocytoma-related hypertension, erectile dysfunction and in the diagnosis of pheochromocytoma and norepinephrine-related dermal necrosis.
    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
  • Biochem/physiol Actions α-Adrenergic receptor antagonist; peripheral vasodilator.
  • Safety Profile Poison by intravenous and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
Phentolamine mesilate Preparation Products And Raw materials
Raw materials
Preparation Products
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65-28-1, Phentolamine mesilateRelated Search:
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  • Phentolamine mesilate for system suitability
  • Phentolamine mesylate, >=99%
  • Phentolamine mesilate(Regitine)
  • regitinemesylate
  • Phentolamine mesylate, ≥98.0%(TLC)
  • regitinmethanesulphonate
  • 2-[N-(M-HYDROXYPHENYL)-P-TOLUIDINOMETHYL]IMIDAZOLINE, METHANESULFONATE
  • 2-(N-[M-HYDROXYPHENYL]-P-TOLUIDINOMETHYL)IMIDAZOLINE METHANESULFONATE SALT
  • 2-[N-(M-HYDROXYPHENYL)-P-TOLUIDINOMETHYL]IMIDAZOLIN METHANESULFONATE SALT
  • 3-[[(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)METHYL](4-METHYLPHENYL)-AMINO]PHENOL MESYLATE
  • 3-[n-(2-imidazolin-2-ylmethyl)-p-toluidino]phenol methanesulphonate
  • PHENOL, 3-(((4,5-DIHYDRO-1H-IMIDAZOL-2-YL)METHYL)(4-METHYLPHENYL)AMINO)-, MONOMETHANESULFONATE (SALT)
  • PhentolamineMesylateCp2000/Usp26Gmp
  • Phentolaminemethanesulfonate,99%
  • PHENTOLAMINEMESYLATE,USP
  • PHENTOLAMINE METHANESULFONATE (PHENTOLAMINE MESYLATE)
  • Phentolamine methanesulfonate salt, 98%, a nonselective alpha-adrenergic antagonist
  • Phentolamine mesilate CRS
  • PhentolamineMesylate&gt
  • Phentolamine for system suitability CRS
  • Phentolaminmesilat
  • Phentolamine mesilate USP/EP/BP
  • 65-28-1
  • C17H19N3OCH4O3SC18H23
  • C17H19N3OCH3SO3H
  • C17H19N3OCH4O3SC18H23N3O4S
  • C17H19N3O.CH4O3S
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