Closantel Structure

Closantel

Chemical Properties

Melting point 217.8°
Boiling point 590.5±50.0 °C(Predicted)
Density  1.8759 (estimate)
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml
form  Solid
pka 5.99±0.48(Predicted)
color  White to off-white
Major Application agriculture
environmental
InChI 1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)
InChIKey JMPFSEBWVLAJKM-UHFFFAOYSA-N
SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c3cc(I)cc(I)c3O
CAS DataBase Reference 57808-65-8(CAS DataBase Reference)
FDA UNII EUL532EI54
UNSPSC Code 41116107
NACRES NA.24

Safety

Symbol(GHS) Skull and Crossbones (GHS06)
Signal wordDanger
Hazard statements H301-H413
Precautionary statements P273-P301+P310+P330
Hazard Codes  Xn
Risk Statements  22
RIDADR  2811
WGK Germany  3
RTECS  CV2444250
HazardClass  6.1(b)
PackingGroup  III
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Aquatic Chronic 4
Toxicity A veterinary drug for the treatment of fluke and nematode infestations. In 1993, some was included in a batch of donated drugs sent to Lithuania. Attempts to match the product with the names of other medicines on accompanying literature resulted in its misidentification as a treatment for endometriosis. Eleven women lost their eyesight; though this has since returned, they were left with eye pain and are unable to work.
NFPA 704:
0
2 0

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