Uses
3-Hydroxybenzophenone is a benzophenone metabolite with potential estrogenic and anti-androgenic activity. is a more attractive hydrogen bonding co-material for MCPBA, as the 3-hydroxyl group is unable to form an intramolecular hydrogen bond. It is commonly used as a radical and cationic photo initiators.
Preparation
Preparation by aromatization of 5-benzoyl-2- cyclohexenone,
? in the presence of 10% Pd/C in refluxing xylene for 6 h (60%)
? in the presence of lithium bromide and cupric bromide in refluxing acetonitrile for 1 h (75%).
