Chemical Properties
Orange powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dried rhizomes of Rhodiola rosea.
Uses
Rhodionin has an effect of nourishing and strengthening, clearing away heat and moistening the lungs.
Biological Activity
Rhodionin, isolated from the roots of Rhodiola crenulata, is a specific, noncompetitive cytochrome P450 2D6 inhibitor with IC50 of 0.761 μM and Ki of 0.769 μM. It has potent DPPH free radical scavenging activity with IC50 of 19.49 μM.
target
IC50: 0.761 μM (cytochrome P450 2D6); 57.50-2.43 μg/mL (AChE); 19.49 μM (DPPH free radical scavenging)
