Description
1-Monomyristin is a 1-monoglyceride with tetradecanoyl (myristoyl) as the acyl group. 1-Monomyristin has a role as a Caenorhabditis elegans metabolite. 1-Monomyristin is a 1-monoglyceride and a tetradecanoate ester.
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans.
Chemical Properties
It is soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from nutmeg.
Uses
α-Monomyristin, is used for the preparation of nonionic surfactant micelles. It is also a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.
Definition
ChEBI: A rac-1-monoacylglycerol that is composed of equal amounts of 1-myristoyl-sn-glycerol and 3-myristoyl-sn-glycerol.
Biological Activity
rac-Glycerol 1-myristate also elicits antifungal activity. It exhibits an anti-proliferative effect in HeLa cervical cancer cells when delivered as a polymeric nanoparticle-based conjugate.', 'rac-Glycerol 1-myristate, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.
IC 50
Human Endogenous Metabolite
