Synthesis
L-Lysine hydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.
Description
A white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble
in alcohol and in ether. It melts at about 260°C with decomposition.
Chemical Properties
White crystalline powder
Uses
L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine.? L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.
Uses
L-(+)-Lysine Monohydrochloride
Uses
amino acid, nutrient
Definition
ChEBI: The hydrochloride salt of L-lysine
Biochem/physiol Actions
L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.
Safety Profile
iWdly toxic by
ingestion. When heated to decomposition it
emits very toxic fumes of HCl and NOx.
Purification Methods
Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]
