Chemical Properties
yellow powder
Uses
5-Nitrosalicylic Acid is a salicylic acid derivative with anti-inflammatory effect against colitis.
Definition
ChEBI: A monohydroxybenzoic acid in which the hydroxy group is ortho- to the carboxylic acid group and which has a nitro substituent para- to the phenolic hydroxy group.
General Description
2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low M
r protein tyrosine phosphatase. The inhibition constant has been evaluated.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise the acid from Me2CO (charcoal), then twice more from Me2CO alone, aqueous EtOH (m 234-236o) or H2O (m 232-233o). [Beilstein 10 III 197, 10 IV 255.]
