Dehydroevodiamine
- Product NameDehydroevodiamine
- CAS67909-49-3
- CBNumberCB51180199
- MFC19H15N3O
- MW301.35
- EINECS200-258-5
- MDL NumberMFCD11656140
- MOL File67909-49-3.mol
- MSDS FileSDS
Chemical Properties
| Melting point | 190-192℃ |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder |
| color | Yellow |
Dehydroevodiamine Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Usbiological 361774 | 20mg | $263 | Dehydroevodiamine |
Buy |
| Biosynth Carbosynth FD74260 | 100mg | $231 | Dehydroevodiamine |
Buy |
| Biorbyt Ltd orb593872 | 100mg | $306 | Dehydroevodiamine |
Buy |
| American Custom Chemicals Corporation INB0002661 | 5MG | $403.06 | 14-METHYL-5-OXO-7,8-DIHYDRO-5H-INDOLO-[2',3',3,4]-PYRIDO[2,1-B]QUINAZOLIN-14-IUM-13-IDE 95.00% |
Buy |
| ChemScene CS-0018627 | 5mg | $50 | Dehydroevodiamine |
Buy |
Dehydroevodiamine Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dried near-ripe fruit of Evodia sclerosus.Uses
Dehydroevodiamine is a novel alkaloid which displays butyrylcholinesterase inhibitory activity in vivo.Biological Activity
Dehydroevodiamine, a quinazoline alkaloid isolated from Evodiae Fructus, has antiarrhythmic effects on guinea pig ventricular myocytes. It inhibits LPS-induced expression of iNOS, COX-2, PGE2 and NF-κB in mouse macrophages.Physiological effects
Dehydroevodiamine has an antihypertensive and antitumor effects.in vitro
Dehydroevodiamine (0-50 μM; 2 hours) inhibits iNOS and COX-2 expression and prevents degradation of IκB-α in LPS induced RAW 264.7 macrophages. Dehydroevodiamine (0-50 μM; 2 hours) inhibits a LPS -induced increase in the iNOS and COX-2 mRNA expression.
Western Blot Analysis
| Cell Line: td> | RAW 264.7 macrophage cells |
| Concentration: | 10 μM, 30 μM, 50 μM |
| Incubation Time: | pretreated 2 hours |
| Result: | Reduced iNOS and COX-2 expression and increased IκB-α expression. |
RT-PCR
| RAW 264.7 macrophage cells | |
| Concentration: | 10 μM, 30 μM, 50 μM | td>
| Incubation Time: | pretreated 2 hours |
| Result: | Reduced iNOS and COX-2 mRNA expression. |
target
| Target | Value |
| NF-κB () | |
| COX-2 () | |
| iNOS () | |
| PGE2 () |
Preparation Products And Raw materials
Dehydroevodiamine Supplier
Global(131)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 | |
| 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 | |
| +8618080483897 | sales@biopurify.com | China | 3772 | 58 | |
| 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 | |
| 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 | |
| +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29811 | 58 | |
| +86-27-8439 4403 18971486879 |
sales@chemnorm.com | CHINA | 2935 | 58 | |
| +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 | |
| 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 | |
| +86-0571-87635730 +8615858229168 |
chem1022@hengdian-group.com | China | 1478 | 58 |
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