Senna

Occurrence

Senna is found throughout the world.

Uses

senna (Cassia angustifolia)(Indian senna, meca senna, tinnevelly senna) is used in traditional medicine as a stimulant. Researchers have isolated a beta-glycan fraction, galactomannan, from the plant’s seeds. The cosmetic properties ascribed to this fraction are similar to those of hyaluronic acid. These include skinsoftening and smoothing properties; a long-term moisturizing effect with an improvement in the stratum corneum’s capacity to hold water; film-forming properties demonstrated by a reduction in transepidermal water loss; and a corrective and repairing ability for dry or rough skin. Senna also acts as an emollient without associated oiliness or leaving an occlusive layer. Its high galactomannan concentration makes senna recommended for skin care preparations designed to relieve or repair dry, rough skin, and for anti-aging cosmetics and moisturizers.

Clinical Use

Constipation

Metabolism

Absorbed senna is metabolised in the liver. Unabsorbed senna is hydrolysed in the colon by bacteria to release the active free anthraquinones.