Chemical Properties
yellow to orange crystalline powder
Uses
4-Nitro-benzeneethanol is a useful synthetic intermediate. It can be used to synthesize N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptor. It can also be used to prepare 2-aza-2''-deoxyinosine-containing oligodeoxyribonucleotide duplexes.
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 2786, 1973
DOI: 10.1021/jo00956a011
General Description
Yellow needles (from aqueous methanol) or orange solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A nitrated alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Health Hazard
SYMPTOMS: Structurally similar chemicals may cause methemoglobinemia.
Fire Hazard
Flash point data for 4-Nitrobenzeneethanol are not available; however, 4-Nitrobenzeneethanol is probably combustible.
