2,4-Diphenyl-6-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,5-triazine

Uses

2,4-Diphenyl-6-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,5-triazine can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.

Synthesis

15.0 g of 2-(3-Bromophenyl)-4,6-diphenyl-l,3,5- triazine (32.4 mmol), 12.3 g of bis(pinacolato)diboron (48.6 mmol), 529 mg of Pd(dppf)Cl2.CH2Cl2 (0.647 mmol), 9.53 g of potassium acetate (97.1 mmol) and 323 ml of dioxane were put into a 1-neck round flask and reacted under reflux at 90° C. for 12 hours. After completion of the reaction, the solvent was removed under reduced pressure. The produced solid was dissolved in dichloromethane and then filtered through a Celite filter and washed with dichloromethane. The solvent was removed under reduced pressure and the resultant compound was crystallized with methanol to obtain 16.0 g of solid compound (intermediate 6) (yield: 96.8%).