Uses
Dopamine receptor antagonist
Uses
S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments.
Biological Activity
Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic.
Biochem/physiol Actions
Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism.
storage
room temperature (desiccate)