Bode Catalyst 1

Uses

(5aS,10bR)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H, 6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride monohydrate can be used as an N-heterocyclic carbene (NHC) organocatalyst:

• In the synthesis of tricyclic β-lactones by reacting 2-bromoenals with 1,3-diketones.
• To functionalize the C2-position of 3-aminobenzofurans using 2-bromoenals as coupling partners.
• In the synthesis of dihydroquinoxalines from substituted bisimines.
• In the preparation of spiro-glutarimide derivatives by reacting cyclic β-ketoamides with α,β-unsaturated aldehydes.