alpha-Boswellic acid (3 or 10 mg/kg, intraperitoneal injection) decreases epidermal thickening, mast cell count and dermal infiltration in BALB/c mice induced by 2, 4-dinitrochlorobenzene[1].
alpha-Boswellic acid (200 mg/kg, gavage) has a protective effect on ethanol-induced gastric injury in rats[2].
| Animal Model: | 2,4-Dinitrochlorobenzene-Induced Atopic-like Dermatitis in BALB/c Mice[1] |
| Dosage: | 3 or 10 mg/kg |
| Administration: | i.p. |
| Result: | Reduced the severity of the AD-like symptoms.
Attenuated the increase in ear thickness and decreased cutaneous TEWL in DNCB-treated mice.
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| Animal Model: | Ethanol-induced gastric injury in rats[2] |
| Dosage: | 200 mg/kg |
| Administration: | i.g. |
| Result: | Reduced injuries associated with the administration of ethanol, gastric juice acidity and the formation of MDA and increased CAT activity and SOD activity and the level of NO and PGE-2 in a dose-depended manner.
Increased the expression of both Nrf2 and HO-1.
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