Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea

Chemical Properties

Uses

• Stereoselective diaryl(nitro)butanone via enantioselective Michael addition of nitromethane to chalcones.
• Enantioselective β-amino acids via asymmetric Mannich reaction of malonates with aryl and alkyl imines.
• The synthesis of 3-indolylmethanamines by the reaction of indoles with imines via asymmetric Friedel-Crafts reaction.
• The enantioselective conjugate addition of active methylene compounds to enones to obtain the corresponding addition products.