2-Iodothiophene

Chemical Properties

colorless to light yellow liquid

Uses

2-Iodothiophene was used in the synthesis of (E)-and (Z)-2,3-difluoro-3-aryl substituted acrylic esters. It was also used as monomer in the preparation of thin conductive films via plasma polymerization of 2-iodothiophene.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 4883, 1995 DOI: 10.1016/0040-4039(95)00876-E

General Description

Mechanism of the fluoride-free, palladium-catalyzed cross-coupling reaction of 2-iodothiophene with potassium (E)-heptenyldimethylsilanolate has been investigated. 2-Iodothiophene participates in microwave-enhanced, rapid homogeneous-phase version of the Sonogashira reaction.