(+)-Medicarpin

Chemical Properties

Soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from S. chinensis.

Uses

(+)-Medicarpin can be used for content determination, identification and pharmacological experiments, etc.

Definition

ChEBI: (+)-medicarpin is the (+)-enantiomer of medicarpin. It is an enantiomer of a (-)-medicarpin.

Biological Activity

(+)-Medicarpin is an isoflavone that can be isolated from several medicinal plants with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, etc. (+)-Medicarpin potently inhibits osteoclastogenesis, and it also promotes bone healing and increases bone mass through osteoblast differentiation through estrogen receptor beta (ERβ)-mediated osteogenesis.