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Lisinopril

Lisinopril Structure
Lisinopril
  • CAS No.83915-83-7
  • Chemical Name:Lisinopril
  • CBNumber:CB3113756
  • Molecular Formula:C21H31N3O5
  • Formula Weight:405.49
  • MOL File:83915-83-7.mol
Lisinopril Property
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H360-H373
  • Precautionary statements P201-P260-P280-P308+P313
Lisinopril Price More Price(10)
  • Brand: Sigma-Aldrich
  • Product number: L6292
  • Product name : Lisinopril
  • Purity: ≥98% (HPLC)
  • Packaging: 100mg
  • Price: $312
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1368609
  • Product name : Lisinopril
  • Purity: United States Pharmacopeia (USP) Reference Standard
  • Packaging: 300mg
  • Price: $352.8
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: L0220
  • Product name : Lisinopril Dihydrate
  • Purity: >98.0%(T)
  • Packaging: 1g
  • Price: $76
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: L0220
  • Product name : Lisinopril Dihydrate
  • Purity: >98.0%(T)
  • Packaging: 5g
  • Price: $228
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: L6292
  • Product name : Lisinopril
  • Purity: ≥98% (HPLC)
  • Packaging: 250mg
  • Price: $691
  • Updated: 2019/12/02
  • Buy: Buy

Lisinopril Chemical Properties,Usage,Production

  • Description Lisinopril is an angiotensin converting enzyme inhibitor structurally related to enalaprilat. It is reportedly useful in the management of hypertension and congestive heart failure.
  • Chemical Properties White to Off-White Crystalline Powder
  • Originator Merck (USA)
  • Uses An orally active angiotensin-converting enzyme (ACE) inhibitor. S,S,S-Isomer of Lisinopril
  • brand name Prinivil (Merck); Zestril (AstraZeneca).
  • General Description Lisinopril, 1-[N2-[S-1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline dihydrate (Prinivil, Zestril), is alysine derivative of enalaprilat, the active metabolite ofenalapril. Like all ACE inhibitors, it is an active site-directedinhibitor of the enzyme, with the zinc ion used in an effectivebinding interaction at a stoichiometric ratio of 1:1. The pharmacologicaleffects of lisinopril are similar to those of captopriland enalapril.
  • Clinical Use Many new ACE inhibitors became available for the treatmentof hypertension following the clinical effectivenessof enalapril. Enalapril is a non–thiol-containing ACE inhibitordevoid of the side effects of rash and loss of thesense of taste characteristic of the thiol-containing compoundcaptopril. With the exception of the phosphoruscontainingfosinopril, these antihypertensive agents havea 2-, like the prototypical drug captopril,are used in the treatment of mild-to-moderate hypertension,either alone or in conjunction with diuretics orcalcium channel blockers.
  • Veterinary Drugs and Treatments The principle uses of lisinopril in veterinary medicine at present are as a vasodilator in the treatment of heart failure or hypertension. Recent studies have demonstrated that ACE inhibitors, particularly when used in conjunction with furosemide, do improve the quality of life in dogs with heart failure. It is not clear, however, whether it has any significant effect on survival times. Lisinopril may also be of benefit in treating the effects associated with valvular heart disease (mitral regurgitation) and left to right shunts. It is being explored as adjunctive treatment in chronic renal failure and in protein losing nephropathies.
    Lisinopril may have advantages over other ACE inhibitors in that it may be dosed once daily and less expensive. Disadvantages are that it is only available in human labeled dosage forms and there is much less published information on its use (efficacy, safety, dosing) in veterinary species.
Lisinopril Preparation Products And Raw materials
Raw materials
Preparation Products
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83915-83-7, LisinoprilRelated Search:
  • Lisinopril Related Compound A (15 mg) ((S)-2-{(3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl}-4-phenylbutanoic acid)
  • (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate
  • LIQUID PRED (prednisone),Lisinopril
  • Lisinopril API
  • Lisinopril (Zestril)
  • N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline,hydrate (1:2)
  • Lisinopril for system suitability
  • Lisinopril for system suitability A
  • Lisinopril for peak identification
  • LISINOPRIL-D5 HYDRATE
  • LISINOPRIL HYDRATE
  • (ds)-1-[n2-(1-carboxy-3-phenylpropyl)-l-prolinedihydrate
  • (s)-1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-l-prolinedihydrate
  • (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521
  • (S) -1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-praline dihydrate
  • L-154826:MK-521
  • Zestfil
  • (2S)-1-[(2S)-6-Amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate
  • (S)-(-)-1-[N-(1-Carboxy-3-phenylpropyl)-L-lysinyl]-L-proline dihydrate
  • Lisinopril,(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521
  • Lisinopril (300 mg)
  • Lisinopril 83915-83-7
  • (2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino] hexanoyl] pyrrole-2-carboxylic acid dihydrate
  • 1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-,dihydrate,(s)-l-prolin
  • renacor
  • N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide dihydrate
  • Lisinopril dihydrate USP24,25 EP2000(III)
  • Lisinopril99%Assay
  • LisinoprilC21H31H305*2H20
  • (S) Lisinopril
  • (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline, Dihydrate, MK-521, Acerbon, Alapril, Carace, Coric, Novatec, Prinil, Prinivil, Tensopril, Vivatec, Zestril
  • (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
  • (S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
  • Lisinopril
  • LISINOPRIL DEHYDRATE
  • (S)-1-{(S)-6-Amino-2-[((S)-1-carboxy-3-phenyl)propylamino]hexanoyl}pyrrolidine-2-carboxylic acid dihydrate
  • 1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
  • LISINOPRI (DIHYDRATE) (LMK-521 (DIHYDRATE))
  • 83915-83-7
  • C21H26N3O5D5
  • C21H35N3O7
  • C21H31N3O5
  • C21H31N3O52H2O
  • C21H31O5N32H2O
  • C13H31N3O52H2O
  • ZESTRIL
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