Description
Trientine hydrochloride is a copper chelating agent recommended for the treatment of Wilson's Disease, especially in patients intolerant of penicillamine therapy.
Unlike the latter agent, trientine is not indicated in cystinuria or rheumatoid arthritis.
Chemical Properties
white crystalline powder
Originator
Cambridge University (United Kingdom)
Uses
Triethylenetetramine Hydrochloride is a selective CuII-chelator; crosslinking agent. Triethylenetetramine is undergoing trials for the treatment of heart failure in patients with diabetes.
Uses
As thermosetting resin; epoxy curing agent; lubricating oil additive; analytical reagent for Cu, Ni.
Definition
ChEBI: Trientine hydrochloride is a secondary amino compound.
brand name
Syprine (Merck);CUPRID.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Trientine Hydrochloride is administered for relief of symptoms of Wilson′s disease for penicillamine intolerance, hence is employed as an oral medication for the treatment of an inherited defect in copper metabolism.
