CD95L

Uses

ED_50?=?1?ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFasL^? recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

Biochem/physiol Actions

Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).