Description
DSG-PEG, MW 2,000 also called PEG-1,2-distearoyl-rac-glycero-3-methylpolyoxyethylene 2000, is used for liposome preparation. DSG-PEG, MW 2,000 has become known for lipid nanoparticle (LNP) preparation for siRNA (small interfering RNA) delivery research.
Uses
DSG-PEG is a type of polyethylene glycol grease. DSG-PEG can be used to prepare liposomes[1].
References
[1] Geng L, et al. Influence of lipid composition of messenger RNA-loaded lipid nanoparticles on the protein expression via intratracheal administration in mice. Int J Pharm. 2023 Apr 25;637:122896. DOI:
10.1016/j.ijpharm.2023.122896[2] DORIEN VAN LYSEBETTEN. Lipid-Polyglutamate Nanoparticle Vaccine Platform[J]. ACS Applied Materials & Interfaces, 2021, 13 5: 6011-6022. DOI:
10.1021/acsami.0c20607
