Mal-PEG1-NHS ester
- Product NameMal-PEG1-NHS ester
- CAS1807518-72-4
- CBNumberCB23062526
- MFC13H14N2O7
- MW310.26
- MDL NumberMFCD26127783
- MOL File1807518-72-4.mol
Chemical Properties
Boiling point | 488.4±55.0 °C(Predicted) |
Density | 1.48±0.1 g/cm3(Predicted) |
solubility | Soluble in DCM |
pka | -2.35±0.20(Predicted) |
form | Solid |
color | White to off-white |
Mal-PEG1-NHS ester Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
BroadPharm BP-21854 | 100mg | $320 | Mal-PEG1-NHSester 98% |
Buy |
BroadPharm BP-21854 | 250mg | $560 | Mal-PEG1-NHSester 98% |
Buy |
Apolloscientific BIPG1502 | 100mg | $623 | Mal-PEG1-NHS ester |
Buy |
BroadPharm BP-21854 | 500mg | $890 | Mal-PEG1-NHSester 98% |
Buy |
ChemScene CS-0107986 | 250mg | $1700 | Mal-PEG1-NHSester |
Buy |
Mal-PEG1-NHS ester Chemical Properties,Usage,Production
Description
Mal-PEG1-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.Biological Activity
Mal-PEG1-NHS ester is a cleavable PEG-based ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PEG-based PROTAC linker that can be used to synthesize PROTACs.in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
Cleavable
| PEGs
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