tBuBrettPhos

Reaction

1. Ligand used in the Pd-catalyzed conversion of aryl and vinyl triflates to bromides and chlorides.
2. Ligand used in the Pd-catalyzed O-arylation of ethyl acetohydroximates.
3. Ligand used in the Pd-catalyzed conversion of aryl chlorides, triflates, and nonaflates to nitroaromatics.
4. Ligand used in the Pd-catalyzed cross-coupling of amides and aryl mesylates.

Uses

Buchwald Phosphine Ligands for chemical Synthesis

General Description

tBuBrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.