(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol

Description

Research results in recent years have shown that sumac extract has a significant inhibitory effect on a variety of tumor cells. Protosappanin B is one of the main components in hematoxylin. It has inhibitory effect on the proliferation of both BTT and T24 cells, and as Protosappanin B acts on each cell for a longer period of time, its killing effect is gradually enhanced, showing a time-dependence.

Chemical Properties

Soluble in methanol, DMSO, insoluble in petroleum ether and other solvents.

Biological Activity

Protosappanin B is a polyphenol extracted from hematoxylin and has anti-tumor effects. In human bladder cancer cells, it can arrest the G1 phase of the cell cycle and induce apoptosis.

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