Uses
Thonzylamine is a selective H1-histamine receptor anatagonists. Tropine esterase inhibitor.
Definition
ChEBI: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes.
General Description
An oily liquid. Used (in the form of the hydrochloride) as an antihistaminic.
Reactivity Profile
thonzylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.
Synthesis
Thonzylamine is synthesized by treating
the sodium salt of 2-(4-methoxybenzyl)aminopyrimidine
with N,N-dimethyl-2-chloroethylamine
.
