Uses
N-Acetylmorpholine is a very important pesticide intermediate. It is one of the main raw materials for the synthesis of agricultural fungicides enoylmorpholine and flumorpholine.
Chemical Properties
CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID
Application
N-acetylmorpholine is a kind of oxaza compound mainly used to synthesize medical disinfectant use in agriculture, Aromatics Extractive Project agents, and gas sweetening agents.
Flammability and Explosibility
Non flammable
Synthesis
Acetic acid and morpholine Reactive Synthesis N-Acetylmorpholine, the first step generates alkylbenzyldimethylasaltsum salts and a strong exothermal reaction; both can carry out under normal temperature, the alkylbenzyldimethylasaltsum saltsum of generation is solid; The dehydration of second step alkylbenzyldimethylasaltsum saltsum generates N-acetyl morphine, is thermo-negative reaction, need at high temperature to carry out, and speed of response is slow. The rate-determining steps of acetic acid and morpholine Reactive Synthesis N-Acetylmorpholine are morpholine dehydration of salt, and high temperature and in time dehydration are favorable to raising the speed of response.
Purification Methods
Distil it through an 8inch Fenske (glass helices packing, p 11) column with a manual take-off head. Purify it by fractional distillation. The hydrobromide has m 172-175o. [Brace J Am Chem Soc 75 357 1953, deBenneville et al. J Org Chem 21 1072 1956, Beilstein 27 III/IV 274.]
