Chemical Properties
white to off-white crystals or crystalline powder
Uses
DL-Norvaline has been used as an internal standard:
- to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
- to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
- for free amino acid analysis in samples of oocytes by liquid chromatography
Uses
DL-Norvaline is a neurotransmitter.
Definition
ChEBI: An alpha-amino acid that is valeric acid which is substituted at position 2 by an amino group.
General Description
DL-Norvaline, a non-protein amino acid, is of significance in metabolic pathways. It is used as a food additive on account of its nutritional and functional characteristics that are beneficial to health.
Biochem/physiol Actions
Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins.
