Description
Terephthalaldehyde is an aromatic dialdehyde. Theoretically, the two aldehydes of terephthalaldehyde (TPA) are equivalent, so the single or double Schiff base from TPA and d-glucosamine (Glc) may be formed at the same time. It is used as an intermediate for the preparation of dyes and fluorescent whitening agents and in the synthesis of polyimines by reacting with aliphatic diamines. It is also used as a precursor for the preparation of paramagnetic microporous polymeric organic frameworks (POFs) through copolymerization with pyrrole, indole, and carbazole. As a good crosslinking agent, it could used in crosslinked chitosan hydrogel for the selective removal of anionic dyes[1].
Chemical Properties
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER
Uses
Terephthalaldehyde (cas# 623-27-8) is a compound useful in organic synthesis.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 3, p. 788, 1955
Tetrahedron Letters, 36, p. 2285, 1995
DOI: 10.1016/0040-4039(95)00191-E
Purification Methods
Terephthalaldehyde [623-27-8] M 134.1, m 116o, b 245 -248o/771mm. Crystallise terephthalaldehyde from water. [Beilstein 7 IV 2140.]
References
[1] Weng Q, et al. Controllable Synthesis and Biological Application of Schiff Bases from d-Glucosamine and Terephthalaldehyde. ACS Omega, 2020; 5: 24864–24870.
