1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT)

Uses

2-?Oleoyl-?1-?palmitoyl-?sn-?glycero-?3-?phospho-?L-?serine Sodium Salt is a reagent that triggered the release of 5-Aminolevulinic acid (5-ALA) from stealth liposomes. A negatively charged membrane lipid.

Uses

Forms negatively charged lipid bilayers. A molecular dynamics simulation indicates that Na⁺ ions penetrate unexpectedly far into the bilayer, well beyond the hydrophilic end groups.

General Description

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Biochem/physiol Actions

Phosphoserine?(PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.