Ilaprazole sodium

Uses

After oral administration, Ilaprazole sodium selectively enters the gastric parietal cells and is converted into an active metabolite of sulfenamide, which interacts with the sulfhydryl group on the H+/K+-ATPase to form a covalent combination of disulfide bonds, irreversibly inhibiting H+/K+- ATPase, which inhibits gastric acid secretion.

in vitro

target

Target	Value
Proton pump ()
H(+) /K(+)-ATPase (in rabbit parietal cell preparation)	6 μM