CGP77675

Uses

CGP77675 has been used in the generation of mouse expanded potential stem cells.

General Description

CGP77675 belongs to the pyrrolopyrimidine class of inhibitors.

Biochem/physiol Actions

CGP77675 is a potent Src kinase inhibitor. CGP77675 is selective toward other protein kinases including Cdc2 (>500-fold), epidermal growth factor (EGF) receptor (7.5-fold), vascular endothelial growth factor receptor (>50-fold), and for v-Abl (15-fold) and focal adhesion kinase (Fak) (>25-fold).