Chemical Properties
Orange-yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from turmeric.
Uses
Dihydrocurcumin has antibacterial, anti-inflammatory, anti-tumor, antioxidant, and hypolipidemic effects.
Biological Activity
Dihydrocurcumin, the major metabolite of curcumin, reduces lipid accumulation and oxidative stress. It can regulate the mRNA and protein levels of SREBP-1C, PNPLA3 and PPARα, increase the protein expression levels of pAKT and PI3K, and reduce the content of intracellular NO and ROS through the Nrf2 signaling pathway.
