N3-PEG3-tBu
- Product NameN3-PEG3-tBu
- CAS252881-73-5
- CBNumberCB12546985
- MFC13H25N3O5
- MW303.3547
- MDL NumberMFCD22201543
- MOL File252881-73-5.mol
- MSDS FileSDS
Chemical Properties
form | Liquid |
color | Colorless to light yellow |
N3-PEG3-tBu Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
TRC A925065 | 1g | $315 | Azido-PEG3-t-butylEster |
Buy |
BroadPharm BP-20637 | 500mg | $320 | Azido-PEG3-t-butylester 98% |
Buy |
BroadPharm BP-20637 | 1g | $440 | Azido-PEG3-t-butylester 98% |
Buy |
ChemPep 280701 | 1g | $449 | N3-PEG3-tBu |
Buy |
AK Scientific AMTGC716 | 5g | $660 | tert-butyl3-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}propanoate |
Buy |
N3-PEG3-tBu Chemical Properties,Usage,Production
Description
Azido-PEG3-t-butyl ester is a click chemistry reagent. The hydrophilic PEG spacer increases solubility in aqueous media. The azide (N3) group canis reactive with alkyne, such as BCN, DBCO via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic conditions.Uses
Azido-PEG3-t-butyl Ester is used as a linker in the conjugation of peptides.Biological Activity
N3-PEG3-tBu is a cleavable ADC linker containing 3-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). It is also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used to synthesize PROTAC molecules.in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
PEGs
| Alkyl/ether
| Cleavable
|
Preparation Products And Raw materials
Preparation Products
N3-PEG3-tBu Supplier
Global(93)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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+18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 | |
028-82550498 | export@pu-kang.com | CHINA | 210 | 58 | |
+86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 | |
+86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 | |
+1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32072 | 58 | |
+8613367258412 | ada@ipurechemical.com | China | 10319 | 58 | |
027-65563561 18717150066 |
3207347307@qq.com | CHINA | 1238 | 58 | |
571-86758373 +8613588754946 |
sales@huarongpharm.com | CHINA | 3148 | 58 | |
+86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19908 | 58 | |
+86-057181025280; +8617767106207 |
sales@molcore.com | China | 49734 | 58 |
252881-73-5, N3-PEG3-tBuRelated Search
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