alpha-aMine-oMega-propionic acid dodecaethylene glycol

Description

Alpha-aMine-oMega-propionic acid dodecaethylene glycol (amino-PEG12-acid) is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Uses

Amino-PEG12-acid, can be used in developing branched polyethyleneimine modified with hyaluronic acid through PEG spacer for targeted anticancer drug delivery.