(S)-7,7Bis[(4S)-(phenyl)oxazol-2-yl)]-2,23,3tetrahydro-1,1spirobiindane, min. 97% (Sa,S,S)-SpiroBOX

Reaction

1. Chiral ligands for copper-catalyzed asymmetric insertions of carbenoids into N–H bond of anilines.
2. Chiral ligands for copper or palladium-catalyzed asymmetric insertions of carbenoids into O–H bond of phenols.
3. Chiral ligands for copper or iron-catalyzed asymmetric insertions of carbenoids into O–H bond of water.
4. Chiral ligands for copper-catalyzed asymmetric insertions of carbenoids into S-H bonds of arylmethylene mercaptans.