ChemicalBook CAS DataBase List Triethylene Glycol 2-Bromoethyl Methyl Ether

Triethylene Glycol 2-Bromoethyl Methyl Ether

Product NameTriethylene Glycol 2-Bromoethyl Methyl Ether
CAS110429-45-3
CBNumberCB12469761
MFC9H19BrO4
MW271.15
MDL NumberMFCD12545963
MOL File110429-45-3.mol
MSDS FileSDS

Chemical Properties

Boiling point	296.3±25.0 °C(Predicted)
Density	1.256±0.06 g/cm3(Predicted)
refractive index	1.4620 to 1.4660
storage temp.	2-8°C
form	clear liquid
color	White to Yellow to Green
CAS DataBase Reference	110429-45-3

Safety

Symbol(GHS)

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352-P305+P351+P338

HS Code

2909.19.6000

NFPA 704:

	0
1		0

Triethylene Glycol 2-Bromoethyl Methyl Ether Price

Product number	Packaging	Price	Product description	Buy
TCI Chemical T2634	5g	$198	Triethylene Glycol 2-Bromoethyl Methyl Ether >95.0%(GC)	Buy
TCI Chemical T2634	25g	$588	Triethylene Glycol 2-Bromoethyl Methyl Ether >95.0%(GC)	Buy
TRC T776665	50mg	$45	Triethylene Glycol 2-Bromoethyl Methyl Ether	Buy
TRC T776665	100mg	$60	Triethylene Glycol 2-Bromoethyl Methyl Ether	Buy
Chem-Impex 41710	5G	$230.72	Triethyleneglycol2-bromoethylmethylether,95%(GC) 95%(GC)	Buy

Triethylene Glycol 2-Bromoethyl Methyl Ether Chemical Properties,Usage,Production

Description

m-PEG4-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

Triethylene Glycol 2-Bromoethyl Methyl Ether is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs) of trastuzumab (HY-P9907). It was placed distal to the monomethyl auristatin E (MMAE) payload to generate ADCs with altered hydrophilicity, antigen binding and in vitro potency. Tetraethylene glycol monotosylate can also be used as a linker of PROTAC, which can be used for the synthesis of PROTAC.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Preparation Products And Raw materials

Triethylene Glycol 2-Bromoethyl Methyl Ether Supplier

Cleavable

PEGs

Supplier	Tel	Email	Country	ProdList	Advantage
9i LLC	+18039569191	MWan@NiNeiLab.com	United States	418	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	13505	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58

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