Description
16-doxyl Stearic acid is a form of stearic acid that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.
Uses
16-DOXYL-stearic acid, free radical is a spin label for membrane fluidity studies. It can be used to study the dynamics of the lipid bilayer, distribution of fatty acids, and effects of lipid components on detergent-resistant membranes. It can be used for the investigation of surfactant effects on protein formulations by EPR spectroscopic technique.
Uses
Involved in membrane studies including:
- Dynamics and state of lipid bilayer-internal water using 1H dynamic nuclear polarization
- Distribution of fatty acids
- Transversal relaxation of nitroxides for PELDOR Spectroscopy
- Effects of different lipid components on detergent-resistant membranes
Definition
ChEBI: 16-DOXYL-stearic acid is a member of aminoxyls. It is functionally related to a 4,4-dimethyloxazolidine-N-oxyl and an octadecanoic acid.
