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Hexamethylphosphoramide Structure

Hexamethylphosphoramide

Chemical Properties

Melting point 7 °C (lit.)
Boiling point 230-232 °C/740 mmHg (lit.)
Density  1.03 g/mL at 25 °C (lit.)
vapor density  6.18 (vs air)
vapor pressure  0.07 mm Hg ( 25 °C)
refractive index  n20/D 1.459(lit.)
Flash point 222 °F
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Soluble), Methanol (Slightly)
pka 4.69±0.70(Predicted)
form  liquid
color  Colorless to light yellow liquid
Odor Spicy odor (no threshold data)
Water Solubility  Miscible
FreezingPoint  7℃
Merck  14,4725
BRN  1099903
Dielectric constant 30.0(20℃)
Stability Stable. Incompatible with strong acids, strong oxidizing agents.
InChIKey GNOIPBMMFNIUFM-UHFFFAOYSA-N
CAS DataBase Reference 680-31-9(CAS DataBase Reference)
EWG's Food Scores 6
FDA UNII M42TU5843Z
Proposition 65 List Hexamethylphosphoramide
IARC 2B (Vol. 15, Sup 7, 71) 1999
NIST Chemistry Reference N,N,N',N',N",N'-Hexamethylphosphorotriamide(680-31-9)
EPA Substance Registry System Hexamethylphosphoramide (680-31-9)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H314-H340-H350
Precautionary statements P202-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  T
Risk Statements  45-46
Safety Statements  53-45-99
RIDADR  2810
WGK Germany  3
RTECS  TD0875000
8
HazardClass  6.1(b)
PackingGroup  III
HS Code  29299090
Hazardous Substances Data 680-31-9(Hazardous Substances Data)
Toxicity LD50 in male, female rats (mg/kg): 2650, 3360 orally (Gaines)
NFPA 704:
1
2 0

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