Molnupiravir
- Product NameMolnupiravir
- CAS2492423-29-5
- CBNumberCB08369543
- MFC13H19N3O7
- MW329.31
- MDL NumberMFCD32663515
- MOL File2492423-29-5.mol
Chemical Properties
Density | 1.62±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO : 100 mg/mL (303.67 mM; Need ultrasonic) |
pka | 6.71±0.20(Predicted) |
FDA UNII | YA84KI1VEW |
Molnupiravir Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
ChemScene CS-0114880 | 200mg | $450 | Molnupiravir 99.94% |
Buy |
ChemScene CS-0114880 | 500mg | $950 | Molnupiravir 99.94% |
Buy |
ChemScene CS-0114880 | 1g | $1550 | Molnupiravir 99.94% |
Buy |
ChemScene CS-0114880 | 25mg | $90 | Molnupiravir 99.94% |
Buy |
ChemScene CS-0114880 | 50mg | $150 | Molnupiravir 99.94% |
Buy |
Molnupiravir Chemical Properties,Usage,Production
Description
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection.Definition
ChEBI: Molnupiravir is a nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N(4)-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19. It has a role as a prodrug, an anticoronaviral agent and an antiviral drug. It is a nucleoside analogue, an isopropyl ester and a ketoxime. It is functionally related to a N(4)-hydroxycytidine.Biological Activity
Molnupiravir is a broad-spectrum antiviral prodrug of the nucleoside analog β-D-N4-hydroxycytidine (NHC). It competes predominantly with CTP for incorporation; it induces lethal viral mutagenesis by increasing G to A and C to U transition mutations without inhibition of RNA synthesis in replicating coronaviruses, which prevents the development of viral resistance. In primary airway epithelial cell cultures, Molnupiravir dose-dependently inhibits SARS-CoV-2 infectious virus production; it also inhibits MERS-CoV and SARS-CoV with EC50 values in the submicromolar range. In mice infected with SARS-CoV or MERS-CoV, it improves pulmonary function, and reduces virus titer and body weight loss. Molnupiravir also displays in vivo efficacy against seasonal and pandemic influenza A shed virus. It is orally bioavailable.storage
Store at -20°CPreparation Products And Raw materials
Molnupiravir Supplier
Global(57)Suppliers
Supplier | Tel | Country | ProdList | Advantage | ||
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+86-571-86088112 | info@proserre.com | China | 1077 | 58 | ||
+1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 | ||
+86-15850508050 +86-15850508050 |
sean.lv@synzest.com | China | 323 | 58 | ||
+86-29-89586680 +86-15129568250 |
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0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 | ||
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admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 20000 | 58 | ||
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0531-58897003 15550412551 |
market@jnchsd.com | China | 208 | 62 | ||
QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9440 | 58 | ||
021-2022843681 15618226720 |
chaolaichem@foxmail.com | China | 6870 | 58 |
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