Chemical Properties
clear colorless liquid
Uses
Methyl trifluoroacetate has been used as reagent for trifluoroacetylation of amines and amino acids.
Synthesis Reference(s)
Journal of the American Chemical Society, 113, p. 700, 1991
DOI: 10.1021/ja00002a063
General Description
Methyl trifluoroacetate along with cesium fluoride or cesium chloride and CuI constitutes a valuable trifluoromethylating reagent for substituting aromatic (or heteroaromatic) iodides and bromides. Adsorption of methyl trifluoroacetate on amorphous silica has been investigated. Fragmentation mechanism of generation of metastable ions from methyl trifluoroacetate has been investigated by mass analyzed ion kinetic energy spectra and ab initio molecular orbital calculations.
Flammability and Explosibility
Flammable
