Chemical Properties
White Solid
Uses
3,7-Dimethyl-1-propargylxanthine (DMPX) has been used as an A
2 -adenosine receptor (AR) antagonist:
- to study its effects on potential modulation of motor output elicited by epidural spinal stimulation (ESS)
- to study the role of A2a?receptor in elevating cyclic adenosine monophosphate (cAMP) levels
- to study its effects on the cell viability of human gastric cancer cell line
Uses
A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM.
Biochem/physiol Actions
3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A2-selective adenosine receptor (AR) antagonist.
