Chemical Properties
1-Acetyl-2-thiourea is a white crystalline solid; forming needles
Chemical Properties
white crystalline powder
Uses
N-Acetylthiourea is a derivative of Thiourea (T375450)
Definition
ChEBI: N-acetylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an acetyl group. It is a member of acetamides and a member of thioureas. It is functionally related to a thiourea.
General Description
White crystalline solid. Noncombustible, but decomposes with heating.
Air & Water Reactions
Slightly soluble in water, soluble in hot water. Hydrolysis occurs rapidly with strong acid/base media.
Reactivity Profile
N-ACETYLTHIOUREA is incompatible with strong oxidizing agents, strong acids and strong bases. Decomposes when heated to give toxic oxides of sulfur and nitrogen.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Potential Exposure
Studied as possible rodenticide; used in organic synthesis.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
Recrystallise the thiourea from AcOH; the solid is washed with Et2O and dried in air then at 100o. [Zahradnik Collect Czech Chem Commun 24 3678 1959, Beilstein 3 IV 354.]
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste Disposal
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.
