ChemicalBook CAS DataBase List 3,3'-IMINODIPROPIONITRILE

3,3'-IMINODIPROPIONITRILE

Product Name3,3'-IMINODIPROPIONITRILE
CAS111-94-4
CBNumberCB0387000
MFC6H9N3
MW123.16
EINECS203-922-3
MDL NumberMFCD00001956
MOL File111-94-4.mol
MSDS FileSDS

Chemical Properties

Melting point	-6 °C
Boiling point	205 °C25 mm Hg(lit.)
Density	1.02 g/mL at 25 °C(lit.)
refractive index	n20/D 1.47(lit.)
Flash point	>230 °F
storage temp.	2-8°C
pka	6.13±0.19(Predicted)
form	clear liquid
color	Colorless to Light yellow to Light orange
Water Solubility	Soluble in water.
Stability	Stable, but moisture sensitive. Reaction with moisture may lead to a build up of pressure in sealed bottles. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	111-94-4(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	3XP1CVU865
EPA Substance Registry System	3,3'-Iminobispropanenitrile (111-94-4)

Safety

Symbol(GHS)

Signal word

Warning

Hazard statements

H315-H319-H301-H318-H335

Precautionary statements

P261-P280a-P301+P310a-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

RIDADR

UN 3334

WGK Germany

RTECS

UG2975000

TSCA

Yes

HS Code

29269095

Hazardous Substances Data

111-94-4(Hazardous Substances Data)

Toxicity

A neurotoxic synthetic nitrile that causes proximal axonopathies in the spinal cord and brain stem. The proximal axonal swellings are due to interruption of slow axonal transport, resulting in a large accumulation of neurofilaments. Secondary to these effects is a progressive atrophy of the distal axon, secondary demyelination, and gliosis. The slow axonal transport defect appears to be selective, as little evidence for perturbations in fast axonal transport have been reported. Behaviorally, IDPN induces hyperactivity, a “waltzing syndrome,” circling and head-rolling in mice and rats. IDPN intoxication has been advanced as a model for certain motor neuron degenerative diseases such as amyotropic lateral sclerosis (ALS) and hereditary canine spinal muscular atrophy (HCSMA).

NFPA 704:

	1
2		0