Synthesis
GENERAL METHOD: 2e-k (4 mmol) was dissolved in diphenyl ether with a catalytic amount of 2-chlorobenzoic acid and heated by microwave radiation at 250°C for 1-2 hours. After completion of the reaction, the reaction mixture was cooled, the precipitate 3e-k was collected by filtration and washed sequentially with hexane and water.
References
[1] Journal of Heterocyclic Chemistry, 2013, vol. 50, # SUPPL.1, p. E1-E8
[2] Nucleosides and Nucleotides, 1996, vol. 15, # 4, p. 889 - 898
[3] Medicinal Chemistry Research, 2016, vol. 25, # 9, p. 1861 - 1876
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 22, p. 6443 - 6450
[5] RSC Advances, 2014, vol. 4, # 12, p. 6254 - 6260
