Description
Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content.
Apigenin 7-O-methylglucuronide which normalized collagen synthesis in OI cells may exert their effects through beta1-integrin-mediated signaling.
Uses
Apigenin 7-O-methylglucuronide is a natural product[1].
References
[1] Harvey A L. Natural products in drug discovery[J]. Drug discovery today, 2008, 13(19-20): 894-901. DOI:
10.1016/j.drudis.2008.07.004