Acediasulfonnatrium

acediasulfone sodium Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Solfone ,Bracco

• Manufacturing Process

  24.8 g of 4,4'-diaminodiphenyl sulfone, 150 g of methyl chloroacetate and 150 ml of ethanol are refluxed together and refluxed for 24 hours. The alcohol and excess methyl chloroacetate are then distilled off on a steam bath under reduced pressure. The residue consisting of the hydrochloride salt of 4-amino- 4'-(carbomethoxymethylamino)diphenyl sulfone is mixed with of alcoholic solution containing 2.5 g lithium hydroxide and refluxed for 4 hours on the steam bath. Most of the alcohol is removed by distillation and the residual lithium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone taken up water. The solution is filtered and dilute HCl added until no more separation occurs. The 4-amino-4'-(carboxymethylamino)diphenyl sulfone thus obtained is collected and dried.
  The sodium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone is prepared by dissolving the free acid in an aqueous solution containing one equivalent of sodium hydroxide and evaporating the solution to dryness in vacuo.

• Therapeutic Function

  Antibacterial

acediasulfone sodium Upstream-Materialien And Downstream Produkte

Acediasulfonnatrium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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