17β-Hydroxyandrost-4-en-3-on-4-methylvalerat

Bezeichnung:17β-Hydroxyandrost-4-en-3-on-4-methylvalerat

Englisch Name:Testosterone isocaproate

CBNumberCB9752601

SummenformelC25H38O3

Molgewicht386.57

Synonyma

17β-Hydroxyandrost-4-en-3-on-4-methylvalerat

17β-Hydroxyandrost-4-en-3-on-4-methylvalerat physikalisch-chemischer Eigenschaften

Schmelzpunkt	79-80 °C
Siedepunkt	487.6±45.0 °C(Predicted)
Dichte	1.07±0.1 g/cm3(Predicted)
Löslichkeit	Practically insoluble in water, very soluble in acetone and in methylene chloride, freely soluble in fatty oils.
InChI	InChI=1/C25H38O3/c1-16(2)5-10-23(27)28-22-9-8-20-19-7-6-17-15-18(26)11-13-24(17,3)21(19)12-14-25(20,22)4/h15-16,19-22H,5-14H2,1-4H3/t19-,20-,21-,22-,24-,25-/s3
InChIKey	PPYHLSBUTAPNGT-BKWLFHPQSA-N
SMILES	[C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCC(C)C \|&1:0,10,12,16,18,21,r\|
CAS Datenbank	15262-86-9(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/21/22-40
S-Sätze:	22-36
WGK Germany	3

Gefahreninformationscode (GHS)

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Testosterone isocaproate is a testosterone ester with improved bioavailability and metabolic half life compared to the endogenous hormone.It used to testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis.
Chemische Eigenschaften
White or almost white powder.
Verwenden
Testosterone Isocaproate is used in the treatment of male hypogonadism (a condition in which the body does not produce enough testosterone).
Definition
ChEBI: Testosterone isocaproate is a steroid ester.
Nebenwirkungen
Acne, Injection site pain, Weight gain, Prostate enlargement, Increased red blood cells, Dizziness, Diarrhea
Mode of action
Testosterone Isocaproate is similar to the natural male hormone, testosterone. Testosterone binds to the androgen receptor (AR), and the ligand-receptor complex translocates to the nucleus and binds to androgen response elements (AREs) on chromosomal DNA, thereby modulating transcription of a set of androgen-responsive genes. Testosterone can also be converted to estrogen and has a similar regulatory action on genes containing estrogen response elements (EREs).